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Chemoprophylaxis After Occupational Exposure to HIV
The Public Health Service has recommended the use of antiretroviral agents as postexposure prophylaxis after certain occupational exposures to HIV. For complete information about the new recommendations, please see "Update: Provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV," MMWR 1996;45:468-72 below. Copies are available from the National AIDS Clearinghouse at 1-800-458-5231.
To collect information about the safety and outcome of taking antiretroviral drugs for postexposure prophylaxis, CDC, Glaxo Wellcome Inc., and Merck & Co. have established the HIV Postexposure Prophylaxis Registry. To learn more about the Registry or to enroll in the Registry, call toll free 888-PEP4HIV (888-737-4448).
Provisional Public Health Service Recommendations For Chemoprophylaxis After Occupational Exposure to HIV
MMWR 45(22);468-472
Although preventing blood exposures is the primary means of preventing occupationally acquired human immunodeficiency virus (HIV) infection, appropriate post-exposure management is an important element of workplace safety (1). Information suggesting that zidovudine (ZDV) postexposure prophylaxis (PEP) may reduce the risk for HIV transmission after occupational exposure to HIV-infected blood (2) prompted a Public Health Service (PHS) interagency working group *, with expert consultation **, to update a previous PHS statement on management of occupational exposure to HIV with the following findings and recommendations on PEP (1). ***
Source: The Centers for Disease Control and Prevention
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