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The bDNA test, developed by Chiron Diagnostics and marketed under the name Quantiplex® HIV-RNA, is based on direct quantification of HIV-1 RNA.
It works by binding branched DNA probes to HIV-1 RNA. This in turn binds enzymes which generates light. The amount of light is measured and is directly related to the amount of HIV-1 RNA in plasma. The bDNA technology can quantitate the major HIV subtypes found worldwide.
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