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Listed below are additional articles that may be helpful in providing answers to questions about protease inhibitors and viral load.
Bartlett, J.G., "Protease inhibitors for HIV infection." Annals of Internal Medicine. 1996; 124:1086-1088.
Carpenter, C.C.J., Fischl, M.A., Hammer, S.M., et al, for the International AIDS Society -USA. "Antiretroviral therapy for HIV infection in 1996." Journal of the American Medical Association. 1996; 276:146-154.
Coombs, R.W., Welles, S.L., Hooper, C., et al. "Association of plasma human immunodeficiency virus type-1 RNA level with risk of clinical progression in patients with advanced infection." Journal of Infectious Diseases. In press.
Collier, A.C., Coombs, R., Schoenfeld, D.A., et al. "Treatment for human immunodeficiency virus infection with saquinivir, zidovudine, and zalcitabine." New England Journal of Medicine. 1996; 334:1011-1017.
Danner, S.A., Carr, A., Leonard, J.M., et al. "A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease." New England Journal of Medicine. 1995; 333:1528-1533.
Goldschmidt, R.H., Moy, A., "Antiretroviral drug treatment for HIV/AIDS." American Family Physician. 1996; Volume 54, Number 2. 574-580.
Gulick, R., Mellors, J., Havlir, D., et al. "Potent and sustained antiretroviral activity of indinavir (IDV) in combination with zidovudine (ZDV) and lamivudine (3TC)." In: Program and Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections; January 28-February 1, 1996. Washington, DC.Abstract LB7.
Havlir, D., Richman, D.D., "Viral dynamics of HIV: implications for drug development and therapeutic strategies." Annals of Internal Medicine. 1996; 124:984-994.
Jacobsen, H., Hanggi, M., Ott, M., et al. "In vivo resistance to an HIV-1 proteinase inhibitor: mutations, kinetics and frequencies." Journal of Infectious Diseases. 1996; 173:1379-1387.
Mellors, J.W., Kinsley, L.A., Rinaldo, C.R.J., et al. "Quantitation of HIV-1 in plasma predicts outcome after seroconversion." Annals of Internal Medicine. 1995; 122:573-579.
Mellors, J.W., Rinaldo, C.R.J., Gupta, P., et al. "Prognosis of HIV-1 infection predicted by the quantity of virus in plasma." Science. 1996; 272:1167-1170.
O'Brien, W.A., Hartigan, P.M., Martin, D., Esinhart, J., "Changes in plasma HIV-1 RNA and CD4+ lymphocyte count relative to treatment and progression to AIDS." New England Journal of Medicine. 1996; 334:426-431.
Saag, M.S., Holodniy, M., Kuritzkes, D.R., et al. "HIV viral load markers in clinical practice: recommendations of an International AIDS Society-USA Expert Panel." Nature Medicine. 1996; 2:625-629.
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