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Drug Cocktail Seems to Eliminate HIV Where It Hides
A new combination of drugs is capable of eliminating all detectable levels of HIV in the body tissues where it is known to reside, researchers say. Previous studies have shown that the drugs can reduce the level of HIV in the bloodstream, but the virus is also known to hide in the tonsils, lymph nodes, spinal fluid, and semen.
Sven Danner, of the University of Amsterdam, and colleagues, report that six patients given a combination of Glaxo Wellcome's AZT and 3TC and Abbott Laboratories' protease inhibitor Norvir had no sign of HIV in their tonsil tissue after six months of treatment. A separate study found that the combination of AZT, 3TC, and Boehringer Ingelheim's drug Viramune had a similar impact on HIV in the lymph tissue of patients who had no detectable HIV in their blood.
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